مگر چندبار به دنيا مي آييم؟ آيا وقت آن نرسيده كه بيشتر مراقب سلامتي مان باشيم؟! سلامتي شامل تامین رفاه کامل جسمی و روانی و اجتماعی انسان است. وزن مناسب از مهمترين اركان سلامتي است. تا زماني كه به سلامتي نرسيده ايم از پا نخواهيم نشست. متاسفانه برخي از افراد با تقليد و دست به دست كردن رژيم دكتر تغذيه،‌ فرصت هاي طلايي كاهش وزن را هدر مي دهند و در اين بين افراد معدودي هستند كه دست به تقليد طراحي رژيم متخصصان ديگر مي زنند بي آنكه از فلسفه و دليل گنجاندن برخي مواد غذايي در رژيم مطلع باشند. خلق را تقليدشان بر باد داد..............اي دوصد لعنت بر اين تقليد باد 

Understanding the role of gut microbes and probiotics in obesity: how far are we

معرفی به دوستان اشتراک گذاری
Understanding the role of gut microbes and probiotics in obesity: how far are we

Pharmacol Res. 2013 Mar;69(1):144-55.
Understanding the role of gut microbes and probiotics in obesity: how far are we?
Sanz Y1, Rastmanesh R, Agostoni C.


Abstract

Obesity has been associated with structural alterations in the gut microbiota, suggesting potential causality between specific microbial taxa and this disorder. Studies in animal models have also provided evidence for plausible gut microbiota mechanisms of action underlying body weight regulation. Yet evidence identifying which specific microbes contribute to or predict obesity is not completely consistent across studies. More recently, diet has also been shown to be primarily involved in regulating the microbiota structure initially related to obesity, suggesting that the role of microbes in energy balance is under the influence of diet. Controversy over the role of components of the gut microbiota in obesity has extended to bacteria, which although weakly related to body weight in observational and human intervention studies, are of interest due to their use as probiotics. This review focuses exclusively on human observational studies and probiotic intervention trials, excluding animal studies and studies in infants at early developmental stages, since such results cannot be extrapolated to human obesity at later stages in life. In this context, evidence for relationships between the gut microbiota composition and obesity and the possible role of probiotics is reviewed, discussing the strengths and weaknesses of the studies conducted to date.


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